Bipolar radiofrequency ablation: The impact of tip load, application duration, power, and indifferent electrode size on the transmurality of a lesion
| 1 | Uniwersytet Medyczny im. K. Marcinkowskiego |
CORRESPONDING AUTHOR
Publication date: 2019-03-21
Heart Beat 2019;4:1–7
KEYWORDS
TOPICS
ABSTRACT
Background:
The main determinant of radiofrequency (RF) ablation effect is transmurality of the lesion. Bipolar radiofrequency ablation (BA) creates transmurality in a higher proportion of cases than unipolar ablation (UA) but little is known about optimal RF settings.
Material and methods:
This study was to compare UA and BA based on different application time, cathode tip load, anode size and power settings for achieving a transmural lesion in vitro. Thermocool electrode was used for ablation (cathode) and 4mm or 8mm tip catheter were used as the ground electrode (anode) for BA. The tested settings were tip-load (10-g and 20-g), power (30W or 40W), and application duration (30, 60, or 90 s). After ablation, we measured scar size and transmurality of the lesion.
Results:
BA created significantly larger and deeper scars compared with UA. Transmurality was achieved respectively in 42% and 2% of cases, (p<0.001). Higher tip load resulted in larger scar size and transmurality was achieved in 37% and 20% cases (p=0.05). Scar size and transmurality increased with RF duration (5%, 39% and 42% of specimens, respectively (p<0.001). Bigger tip size of ground electrode was related to higher transmurality (22% vs 61% , p<0.001). No relationship was between power and transmurality. Optimal parameter settings were 20-g tip load, indifferent electrode with 8-mm tip, and 90-s RF duration (97.6% transmurality).
Conclusions:
BA is more effective than UA in achieving transmural lesions. Optimal settings for BA consist of longer RF duration, higher tip load, and bigger tip size of indifferent electrode.
The main determinant of radiofrequency (RF) ablation effect is transmurality of the lesion. Bipolar radiofrequency ablation (BA) creates transmurality in a higher proportion of cases than unipolar ablation (UA) but little is known about optimal RF settings.
Material and methods:
This study was to compare UA and BA based on different application time, cathode tip load, anode size and power settings for achieving a transmural lesion in vitro. Thermocool electrode was used for ablation (cathode) and 4mm or 8mm tip catheter were used as the ground electrode (anode) for BA. The tested settings were tip-load (10-g and 20-g), power (30W or 40W), and application duration (30, 60, or 90 s). After ablation, we measured scar size and transmurality of the lesion.
Results:
BA created significantly larger and deeper scars compared with UA. Transmurality was achieved respectively in 42% and 2% of cases, (p<0.001). Higher tip load resulted in larger scar size and transmurality was achieved in 37% and 20% cases (p=0.05). Scar size and transmurality increased with RF duration (5%, 39% and 42% of specimens, respectively (p<0.001). Bigger tip size of ground electrode was related to higher transmurality (22% vs 61% , p<0.001). No relationship was between power and transmurality. Optimal parameter settings were 20-g tip load, indifferent electrode with 8-mm tip, and 90-s RF duration (97.6% transmurality).
Conclusions:
BA is more effective than UA in achieving transmural lesions. Optimal settings for BA consist of longer RF duration, higher tip load, and bigger tip size of indifferent electrode.
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